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All patients were visited monthly, their blood glucose and creatinine were controlled monthly by experiments and if any problems or side effects were seen, patients were excluded from study. After four months the examinations were performed again. Initial and four months laboratory tests were conducted using Pars Azmoon lab kits (TG91008, ""type"":""entrez-protein"",""attrs"":""text"":""CHL91012"",""term_id"":""813236495"",""term_text"":""CHL91012""CHL91012, CRP92002, LDL-""type"":""entrez-nucleotide"",""attrs"":""text"":""C92004"",""term_id"":""3073880"",""term_text"":""C92004""C92004, [http://en.wikipedia.org/wiki/MRIP MRIP] HDL-""type"":""entrez-nucleotide"",""attrs"":""text"":""C92002"",""term_id"":""3073878"",""term_text"":""C92002""C92002, and Glu92008) at Labbafinejad hospital laboratory. 3.3. Ethical issues (a) [http://www.selleckchem.com/products/Temsirolimus.html Temsirolimus chemical structure] The research followed the tenets of the Declaration of Helsinki; (b) informed consent was obtained; and (c) the research was approved by the Urology and Nephrology Research Center and ethics committee of Shahid-Beheshti University of Medical Sciences and also has Iranian registry of clinical trials code of IRCT2014050117413N2. 3.4. Statistical analysis Data were analyzed by SPSS version 21 (SPSS Inc. Chicago, IL) for windows. At first, study patients described using mean descriptive statistics, standard deviation, and frequency then two groups compared before intervention by independent sample t test and its nonparametric equivalent (Mann-Whitney) for quantitative variables, then Chi2 and Fisher exact tests used for qualitative variables. After treatment, groups wrer compared with above tests. Then before and after treatment amounts were compared in each group with paired sample t test, its nonparametric equivalent (Wilcoxon), and McNemar test. A, P amount less than 0.05 considered as significant value. 4. Results A total of 58 patients were studied (29 patients in each group). Sixty-nine percent of group A were male and 31% were female. This distribution was 62 males and 38% female in group B (P = 0.58). The mean age was 44.15 �� 13.82 years that was 44.41 �� 14.24 years in group A and 43.68 �� 13.67 years in group B (P = 0.89). The mean weight was 78.73 �� 11.39 kg and the mean BMI was 28.32 �� 3.76 kg/m2 (Table 1). Table 1 Comparison of characteristics and laboratory findings before and after treatment between groups The mean body weight was increased [http://www.selleckchem.com/products/PD-173074.html PD173074 nmr] 2.09 �� 1.8 kg in group A and decreased 1.45 �� 2.21 kg in group B (P