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P-values [https://en.wikipedia.org/wiki/Dabigatran Dabigatran] to the control group) (11). [http://www.selleckchem.com/products/Bosutinib.html this website] Properdin levels in the healthy volunteers of European background analyzed as part of this study were higher than those reported in a recent study for healthy South East Asians (12). Table 1 Properdin levels in sera of critically ill patients with sepsis admitted to ICU and a healthy control group. The overall 30-day mortality in patients was 21/81 (25.9%). For four patients, in whom there (reproducibly) was no antigenically detectable properdin in their initial serum samples, no subsequent sample existed to exclude a genetic deficiency. But, as properdin is an x-chromosome linked gene and a primary deficiency uncommon, the possibility of a gene defect does not appear likely in the case of the two female patients. When comparing properdin levels determined for samples obtained on day 1 of admission to ICU between survivors and non-survivors, properdin appeared to be lower in non-survivors but this did not reach statistical significance (Table ?(Table11). Properdin levels determined on day 1 of ICU admission did not relate to APACHE or SOFA scores (data not shown) or duration of stay in ICU or in hospital, but for the whole group, the ICU stay correlated significantly with hospital stay (80 pairs analyzed, r?=?0.6, p?[http://www.selleckchem.com/products/byl719.html Akt inhibitor] decreased C3 levels were linked to increased hospital stay (14). Therefore, a subgroup analysis was performed for very low properdin levels. These were defined as