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Intubation failure was defined as follows: intubation time longer than 40 seconds, the insertion of the endotracheal tube into the esophagus of the manikin, and removal of the endotracheal tube from the manikin's mouth before successful intubation. In previous similar studies, intubation failure was defined as 60 to 120 seconds [11], [12]?and?[13]. However, performers intubating in an emergency [http://en.wikipedia.org/wiki/UGT1A7 UGT1A7] would not have this amount of time. Therefore, we decided to regard a tracheal intubation time of less than 40 seconds as a successful intubation for our discussion of the average intubation time of the McGrath series 5 [11], [12]?and?[13]. Other secondary outcomes included the rate of successful intubation and the Cormack-Lehane grade at laryngoscopy. We based our minimum sample size estimate on the duration of the successful intubation attempts. Our sample size was calculated using informal pilot data generated by the research team. In the pilot study, the mean intubation times for the McGrath MAC and the GlidesScope Ranger were 31 and 24 seconds, respectively, with an SD of 8 seconds. Based on these figures and using �� = .05 and �� = .2 for an experimental design examining 2 devices, we estimated that at least 28 novices would be required to detect a 7-second difference. The results were analyzed using SPSS statistical software, version 20 (IBM Corp, New York, NY). The outcome from each participant was dependent on the time factor of intubation attempts. Therefore, the analysis of the time [http://www.selleckchem.com/products/r428.html R428] to intubation and the rate for successful intubation was performed using repeated-measures analysis of variance (ANOVA). The Kruskal-Wallis test was performed to compare the overall glottic view from all 3 devices. The Mann-Whitney U test was used as a posttest for all variables. The posttest was performed with a Bonferroni correction for the repeated-measures ANOVA when evaluating the intubation time and the success rate of each intubation [http://www.selleckchem.com/products/PF-2341066.html Crizotinib supplier] attempt. For all statistical analyses, P
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