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026), especially in the medium and the fast playing conditions (M = 0.045). Using both effectors in a coordinated fashion (tongue + fingers) stabilized the timing error (M = 0.013), but showed a significant tempo reduction in the fast tempo condition (M = 0.058). We observed a learning effect in the recording of the second trial for [http://www.selleckchem.com/products/dabrafenib-gsk2118436.html GSK2118436] the same task [F(1, 17) = 6.55, p  error for combined tongue-finger actions at medium and fast tempi was significantly reduced in the second trial. This indicates that professional players already improved their tongue-finger coordination after the first 6 repetitions and were able to perform the second trial with reduced timing error. Figure 6 Timing error (A) and coefficient of variation (B), grouped by effectors used to produce tone onsets. Error bars show the standard error of the mean. Table 1 Timing error for both trials of sequences performed with different effectors in three tempo conditions. A Two-Way repeated measures ANOVA on temporal precision (CV) by effector combination and tempo, showed a significant effect of tempo [F(2, 34) = 5.76, p  at the CV values plotted in Figure ?Figure6B6B (dotted line), we see that timing precision for [http://www.selleckchem.com/products/PD-0332991.html PD-332991] the finger-only [http://en.wikipedia.org/wiki/Megestrol_acetate Megestrol Acetate] condition was lower in the slow tempo condition than in the fast tempo condition. A similar pattern appeared for the tongue-finger condition. Contrary, tones played only by tonguing (solid line) showed almost a constant irregularity over all three tempo conditions. This was confirmed by three separate One-Way repeated measures ANOVAs on the CV by tempo condition. The results showed a significant main effect of tempo for both conditions where fingers were involved [fingers only: F(2, 34) = 13.25, p