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R0 resection was defined by the complete tumor excision after surgical treatment proved by pathologic examination of the resected margins. Clinicopathological parameters, including gender and age of patients; location of the tumor; depth of invasion; LN metastasis status; operative details; morbidity and mortality; and survival and recurrence were collected. Patients with synchronous malignancies, and those who were diagnosed others than adenocarcinoma was excluded from the study. We did not use endoscopic ultrasound in our center. During the study period, the median survival for patients who did not undergo surgery and only had palliative management was 6 mo. All patients did not receive a preoperative adjuvant or neoadjuvant therapy. Cancer staging was as described in the seventh edition [https://en.wikipedia.org/wiki/Itraconazole Itraconazole] of the International Union Against Cancer TNM Classification[9]. All of the surgical procedures were performed by experienced gastric surgeons of our single institute with a definitive treatment guideline for gastric cancer. Two types of gastrectomy were performed: Subtotal gastrectomy (STG) or total gastrectomy (TG). STG was performed for tumors located in the lower and middle third of the stomach when a 3-6 cm tumor proximal free safety margin can be achieved. All the other patients underwent TG. STG includes the removal of the greater and lesser omentum. The first portion of the duodenum was mobilized and divided at least 2 cm distal to the pylorus with at least 2 cm distal safety margin. The left gastric artery was ligated at its origin. A roux-en-Y reconstruction was done for 18 patients who left with [http://www.selleckchem.com/products/Verteporfin(Visudyne).html Verteporfin in vitro] small gastric pouches ([http://www.selleckchem.com/products/Vandetanib.html Vandetanib chemical structure] All patients did not receive adjuvant or neoadjuvant therapy. Statistical analysis The ��2 or Fisher��s exact test was used to compare categorical variables. Survival was calculated using the Kaplan Meyer method and groups were compared using the Log-Rank test. Factors that were deemed of potential importance on univariate analysis were included in the multivariate analysis. A probability (P) of less than 0.05 (two sided) was considered statistically significant. Overall mortality represented all deaths during follow-up. Cox multivariate proportional hazards regression models were used to assess the overall survival power of these parameters. All analyses were done using SPSS? software program version 21 (Chicago, United States). RESULTS From February 2009 to February 2013, eighty patients with gastric carcinoma were managed in our Gastroenterology Surgical Center.