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17 (SD?=?18.62), consistent with severe levels of PTSD.[19] Heavy stimulant users had significantly higher total PTSD severity scores than light users (M?=?69.31; SD?=?18.47 vs. M?=?61.92; SD?=?18.19, respectively, t?=?2.38, p?=?.02). Heavy stimulant users also had significantly higher avoidance/numbing scores compared with light stimulant users (M?=?29.15; SD?=?8.71 vs. M?=?25.39; SD?=?10.04, respectively, t?=?2.33, p?=?.02). The final mixed effect analysis revealed no significant treatment effect on total PTSD severity scores during follow-up (��2 (1)?=?.99, p?=?.32; see Table 2) nor any significant effect of baseline levels of stimulant use (heavy vs. light use) on total PTSD severity scores during follow-up (��2 (1)?=?.07, p?=?.79). [http://www.selleckchem.com/products/PD-0332991.html selleck screening library] Significant effects included time (��2 (3)?=?10.26, p?=?.017) and baseline total PTSD severity scores (��2 (1)?=?14.82, p??.05), nor any significant effects of baseline levels [http://www.selleckchem.com/products/dabrafenib-gsk2118436.html this website] of stimulant use on PTSD symptom cluster scores during follow-up (p?>?.05). The [http://en.wikipedia.org/wiki/Megestrol_acetate Megestrol Acetate] generalized multinomial logistic mixed effects model revealed there was no significant main effect of treatment condition on stimulant use frequency during follow-up (��2 (1)?=?1.13, p?=?.29). Both treatment conditions demonstrated significant reductions in frequency of stimulant use at post-treatment follow-ups (see Table 2). There was a significant three-way interaction among baseline stimulant use, treatment group, and total PTSD symptoms improvement from baseline to each follow-up time point (��2 (1)?=?7.00, p?