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		<title>Butane3area : Page créée avec « An antibiogram was also carried out, following the guidelines of the Antibiogramme Committee of the French Society for Microbiology (CA-SFM). An antifungigram was systemat... »</title>
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				<updated>2017-02-22T01:27:35Z</updated>
		
		<summary type="html">&lt;p&gt;Page créée avec « An antibiogram was also carried out, following the guidelines of the Antibiogramme Committee of the French Society for Microbiology (CA-SFM). An antifungigram was systemat... »&lt;/p&gt;
&lt;p&gt;&lt;b&gt;Nouvelle page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;An antibiogram was also carried out, following the guidelines of the Antibiogramme Committee of the French Society for Microbiology (CA-SFM). An antifungigram was systematically carried out using the E-test? technique (BioM��rieux?), whenever the isolate contained a fungus. The inhibition zone or E-test? diameters were read by a SIRSCAN? analyzer (i2a?, Perols, France). The data were gathered using the ��epidemiological�� module of the SIR? software (i2a?), with individualized analyses of [http://en.wikipedia.org/wiki/PRDX5 PRDX5] the species and their resistance profiles. The bacteria belonging to commensal flora (coagulase-negative staphylococcus and Corynebacteria sp.) were retained if they were isolated at least twice with the same antibiotype. Duplicates (even isolates with the same sensitivity [http://www.selleckchem.com/products/midostaurin-pkc412.html Selleck Midostaurin] profile, isolated several times in the same patient over a period of at least 5?days) were excluded. The colistin�Camphotericin B combination is used in our hospital for selective digestive decontamination (SDD). During allogeneic bone marrow transplantation (BMT), patients receive primary antibioprophylaxis based on a combination of ciprofloxacin and a piperacillin/tazobactam. In the case of febrile neutropenia, the most urgent issue is antibacterial therapy, based on an empirical broad-spectrum antibiotherapy. The protocol applied in our haematology department relies on a dual empirical antibiotherapy according to the Infectious Diseases Society of America (piperacillin/tazobactam and amikacin) for 3?days [5]. The combination with aminoglycoside is not recommended by the European Conference on Infection [http://www.selleckchem.com/products/mcc950-sodium-salt.html see more] in Leukemia unless septic shock or pneumonia occurs [6]. In the case of persistent fever, antibacterial therapy relies on ceftazidime and vancomycin and amikacin. This first-line treatment regimen is maintained if effective and/or if the isolated bacterial species is sensitive to this combination. If a resistant GNB is isolated, the spectrum is enlarged to include third-generation cephalosporins (3GC) or even imipenem in the case of ESBL (extended-spectrum betalactamase-producing enterobacteria), which hydrolyze 3GC. If a GPC is isolated, vancomycin is given. This antibiotic can be added at an early stage in the case of an MRSA-carrier patient. Finally, the addition of an antifungal drug (amphotericin B) can become necessary if a fungal infection is isolated or suspected. Over an 8-year period, 1413 patients were hospitalized in our haematology department. Of these, 829 had neutropenia with&lt;/div&gt;</summary>
		<author><name>Butane3area</name></author>	</entry>

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