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− | + | Their application to clinical diagnosis may be performed in large-scale studies, with consideration to cost-effectiveness in the future. Footnotes Author contributions All authors made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; took part in either drafting the article or revising it critically for important intellectual content; gave final approval of the version to be published; and agree to be accountable for all aspects of the work. Disclosure The authors report no conflicts of interest in this work.""In developed countries, atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with an exponential increase with advancing age.1 It is strongly associated with an increased risk of [http://en.wikipedia.org/wiki/PFKM PFKM] stroke, hospitalization, and mortality.2 With the existing epidemiological transition from communicable to noncommunicable diseases, AF is a growing public health problem in sub-Saharan Africa (SSA).3 Use of anticoagulants, accessibility and costs of monitoring, poor drug compliance, [http://www.selleckchem.com/products/BMS-754807.html BMS-754807 datasheet] and nonadherence to existing treatment guidelines are key challenges in managing patients with AF in this region.4,5 Data derived from studies in SSA in comparison to those derived from the developed countries have revealed that majority of patients presenting with AF have very severe disease and are comparatively younger with a higher frequency of concomitant complications.6�C10 In Uganda, there is no literature on the clinical profile, complications, and outcome of patients presenting with AF. This was the basis of performing this contemporary cross-sectional study to describe the clinical characteristics and complications of patients presenting with AF at the cardiology unit of Mulago National Referral and Teaching Hospital, Kampala, Uganda. Study methods This was a descriptive cross-sectional study performed at the cardiology unit of Mulago National Referral and Teaching hospital in Kampala, the capital city of Uganda. This is the largest national referral hospital, teaching and health care research facility [http://www.selleckchem.com/products/blz945.html BLZ945] in Uganda with a 1,600 bed capacity. Eligible patients presenting with AF to the cardiology unit, who were ��13 years old, and had offered written informed consent or assent were consecutively recruited over a period of 3 months (April to June 2012) until the desired sample size was attained. Caregivers of patients |
Version du 27 février 2017 à 07:53
Their application to clinical diagnosis may be performed in large-scale studies, with consideration to cost-effectiveness in the future. Footnotes Author contributions All authors made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; took part in either drafting the article or revising it critically for important intellectual content; gave final approval of the version to be published; and agree to be accountable for all aspects of the work. Disclosure The authors report no conflicts of interest in this work.""In developed countries, atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with an exponential increase with advancing age.1 It is strongly associated with an increased risk of PFKM stroke, hospitalization, and mortality.2 With the existing epidemiological transition from communicable to noncommunicable diseases, AF is a growing public health problem in sub-Saharan Africa (SSA).3 Use of anticoagulants, accessibility and costs of monitoring, poor drug compliance, BMS-754807 datasheet and nonadherence to existing treatment guidelines are key challenges in managing patients with AF in this region.4,5 Data derived from studies in SSA in comparison to those derived from the developed countries have revealed that majority of patients presenting with AF have very severe disease and are comparatively younger with a higher frequency of concomitant complications.6�C10 In Uganda, there is no literature on the clinical profile, complications, and outcome of patients presenting with AF. This was the basis of performing this contemporary cross-sectional study to describe the clinical characteristics and complications of patients presenting with AF at the cardiology unit of Mulago National Referral and Teaching Hospital, Kampala, Uganda. Study methods This was a descriptive cross-sectional study performed at the cardiology unit of Mulago National Referral and Teaching hospital in Kampala, the capital city of Uganda. This is the largest national referral hospital, teaching and health care research facility BLZ945 in Uganda with a 1,600 bed capacity. Eligible patients presenting with AF to the cardiology unit, who were ��13 years old, and had offered written informed consent or assent were consecutively recruited over a period of 3 months (April to June 2012) until the desired sample size was attained. Caregivers of patients