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If the predisposing factors are the same for a single cellulitis episode and for recurrences, one would expect PH patients to be older than NH patients. In two previous studies, this was indeed the case, in contrast to our findings [8,13]. However, up to 50% of NH patients may suffer a recurrence [14,16] and thus actually belong to the PH group, a fact that detracts from the validity of the conclusions. This issue will be addressed in a subsequent follow-up study. The LOS in hospital E-64 is determined by the subjective decision of the treating physician, and obviously depends on clinical signs of disease activity. It may also depend on the age and social circumstances of the patient, as well as on comorbidities [17,18]. In the present study, the LOS was associated with recurrent cellulitis independently of the age or diabetic status of the patient. In conclusion, the present findings support those of earlier case�Ccontrol studies, in that chronic oedema, disruption of the cutaneous barrier and obesity proved to be risk factors for hospitalization due to acute non-necrotizing cellulitis. In addition, obesity and a previous ipsilateral surgical procedure were statistically significantly more common in patients with a PH of cellulitis, whereas a recent (JQ1 research buy thanked. We also thank research nurse P. Aitos (University of Helsinki) for excellent technical assistance, and S. Massinen (University of Helsinki) and S. V?h?kuopus (National Public Health Institute) for helpful discussions. This study was presented in part at the 18th European Congress of Clinical Microbiology and Infectious Diseases, Barcelona, Spain, April 2008 (poster number P1621). This study was supported by grants from the Academy of Finland/MICMAN Research programme 2003�C2005, and the Competitive buy R428 Research Funding of the Pirkanmaa Hospital District, Tampere University Hospital. All authors declare no conflicts of interest. ""Few data are available on treatment and outcome of methicillin-resistant (MR) staphylococcal prosthetic joint infections. Vancomycin remains the treatment of choice for these infections, but its efficacy and safety in bone-and-joint infections are insufficiently documented. We conducted a prospective cohort study on 60 patients treated between November 2002 and December 2008 for chronic MR staphylococcal (44 S.?epidermidis, nine other coagulase-negative Staphylococcus and seven S.?aureus) prosthetic hip infections (PHIs). Twenty-two patients had previously undergone surgery for their PHI and 21 had previously received antibiotics.