ALG1 Signifies On Its Own, Plans An Arctic Holiday Retreat

Periodontal probing depth, BOP and GCF flow showed a significant increase between T1 and T2 and a reduction between T2 and T3, resulting in the absence of significant differences between T3 and T1, except for BOP at banded sites. Placement of fixed appliances has an impact on periodontal parameters. The results showed that not all parameters were normalized 740 Y-P research buy at T3, indicating that the changes are only partially reversible. Fixed orthodontic treatment is the method of choice in contemporary orthodontics. The placement of orthodontic bands and brackets may compromise an optimal oral hygiene, resulting in accumulation and maturation of dental plaque [1-4]. It is well established that bacterial plaque is the primary etiological factor in the development of gingival inflammation and periodontitis [5-7]. A systematic review on the effects of orthodontic treatment on periodontal health identified an absence of reliable evidence on this topic. The existing low-quality evidence suggests that orthodontic treatment results in small detrimental effects to the periodontium. The relative short-term follow-up does selleck chemicals llc not allow to extrapolate the long-term effects of orthodontic appliances on periodontal parameters [8, 9]. In a previous study, it was reported that the clinical periodontal values (PPD, BOP and GCF flow) and microbiology tended to normalize after debonding, but most values remained significantly elevated 3�months after debonding compared with baseline [10]. As the periodontal parameters only partly normalized 3�months after debonding, repeating these measurements after a longer period of time was recommended to elucidate long-term changes. Therefore, the aims of this ALG1 longitudinal prospective study were to investigate microbial and clinical periodontal changes after placement of orthodontic bands and brackets and to determine whether or not these parameters further normalize 2�years after termination of the orthodontic treatment by means of fixed appliances. Twenty-four patients (10 males, 14 females), aged 14.6��?.1?years, referred to the Department of Orthodontics of the University Hospital Leuven, were included. All patients fulfilled the following inclusion criteria: no systemic disease, non-smoker, absence of extensive dental restorations, or adhesive fixed partial dentures, a sulcus bleeding index