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The least and most scores, in any dimension, were 0 and 100, respectively. This questionnaire has been prepared and compiled through the cooperation of 15 international departments in order to be used in different cultures.15 In addition; its validity has been approved in the study performed by Yousefy et al. in Iran.16 The Coopersmith Self-esteem Inventory (CSEI) was applied to study patients' self-esteem level. This inventory is one of the most famous instruments in measuring self-esteem and has been used frequently. This scale consists of 58 questions 26 of which were related to general, social, familial, and professional issues. In addition, 8 questions were specified for fake replies which, in fact, are considered as a sign of a defensive reaction toward the questionnaire. Therefore, the lowest and highest scores are 0 and 50, respectively. The closer the score Entinostat clinical trial is to 50, the higher the level of self-esteem and vice versa. The test-retest Mianserin HCl reliability coefficients of the CSEI have been respectively reported as 0.91 and 0.73. The validity and constancy of this instrument has been found to be 92% in previous research which reflects the constancy, reproducibility, and accuracy of this instrument.17 Delaram et al. calculated the validity of the CSEI by test-retest method at 90% and 93%, respectively.18 Data were analyzed by descriptive-analytical statistics and using SPSS for Windows (version 15; SPSS Inc., Chicago, IL, USA). Chi-square test was used to compare the relationship between self-esteem and quality of life in patients with ITP. Results The results showed that 32% of patients were 36 and older, 59% were female and 26.6% had primary education. The majority of ITP patients (29.7%) had low self-esteem and quality of life. Chi-square test showed a significant relationship between self-esteem and quality of life of ITP patients (p = 0.03) (Table 1). Pearson��s correlation coefficient showed no significant relationship between mean total score of self-esteem of patients and their demographic variables (age, hospitalization frequency). However, it showed a significant relationship between self-esteem and duration of illness (r = 0.26, p DNA Synthesis inhibitor factors in the flourishing of talent and creativity. In other words, cognitive process, feelings, motivation, decision making and selection are all affected by the feeling of self-respect. Low self-esteem, especially in chronic diseases, has a negative impact on patients' interpersonal relations, thoughts, feelings, and functioning.19 Most subjects, in present study, were older than 36 and female. The results of the study by Zhou et al. showed that 77% of the studied subjects were female and their average age was 45 years.
