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Nearly as frequent was C.?concisus with 400 patients (median 52?years; IQR 21�C68?years) corresponding to an average annual incidence of 35/100?000 inhabitants. There was a very low prevalence of other non-thermophilic Campylobacter species and C.?curvus (n?=?5) PARP cancer and C.?upsaliensis (n?=?2) were the only ones cultivated in this study. We also cultivated one isolate of the close-related Arcobacter cryaerophilus (using the MALDI-TOF (matrix-assisted laser desorption/ionization-time of flight) Biotyper for identification, data not shown). One hundred and forty (35%) patients infected with C.?concisus were hospitalized and 260 patients were seen in general practice. Only 102 (21%) patients infected with C.?jejuni/coli were hospitalized. For both Campylobacter groups there was a similar hospitalization rate (data not shown) in all age groups, and half of all elderly patients were hospitalized. No Campylobacteraceae was cultured in stool samples from healthy volunteers (median 14?years; range 0�C69?years, with equal sex ratio). Co-infections with Clostridium difficile were twice as frequent in C.?concisus-infected patients (n?=?22) compared with patients with C.?jejuni/coli (n?=?11) and concurrent detection of Salmonella enterica was even higher with more than triple frequency in C.?concisus patients (n?=?18) compared with patients with C.?jejuni/coli (n?=?5). Two patients had C.?concisus as well as C.?jejuni/coli in their faecal sample, and three C.?concisus patients had co-infections with Plesiomonas shigelloides, Yersinia enterocolitica, or Shigella sonnei, Thalidomide respectively. Both C.?concisus PCI-32765 in vivo and C.?jejuni/coli were isolated from patients of all ages; however, the age-specific incidences showed that C.?concisus as well as C.?jejuni/coli were frequent among toddlers. Campylobacter concisus was also frequent among very small children (