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The items in this questionnaire refer to the severity of psychological symptoms during the past week. Each item of the SCL-90-R is rated on a 5-point (0�C4) scale of distress ranging from not-at-all to extremely. Although the SCL-90-R is not disorder-based, the symptoms cluster along nine symptom dimensions including somatization, obsessive-compulsive disorder, depression, anxiety, phobic anxiety, hostility, interpersonal sensitivity, paranoid ideation, and psychoticism. Elevated scores on each of the subscales indicate possible psychopathology. It takes approximately 15�C20 min to complete.[7,8] The dimensional structure of the SCL-90-R is demonstrated in Table 1.[8] Table 1 Dimensional structure of SCL-90-R Participants were asked to include their gender and age on questionnaires but Adenine not their first/last names. They were reassured that their test results would be kept strictly confidential. Interpretation of the SCL-90-R focuses on both the total score (with a higher score showing more severe psychopathology) and the subscale Target Selective Inhibitor Library solubility dmso scores. In depression, average score of above 3 shows severe depression with psychotic features. Moreover, there are three global indices which can be calculated from the raw scores on the questionnaire: (1) The global severity index (GSI), a weighted frequency score based on the sum of the ratings the patient has assigned to each symptom; (2) the positive symptom total (PST), a frequency count of the number of symptoms the patient has reported; and (3) the positive symptom distress index (PSDI), a score reflecting the intensity of distress corrected for the number of symptoms endorsed.[7,8,9] The data obtained were coded and analyzed using SPSS 11.5 Windows (? SPSS Inc., Chicago, IL, USA). The value of significant difference was set at P click here age was 41/36 �� 13/40 years (16�C70 years) in the case group and 31/85 �� 12/72 years (19�C66 years) in the control group. Mann�CWhitney test showed that there was a significant age difference between case and control groups (P = 0.00). So, standard multivariate regression analysis was done to adjust age between the two groups. The average scores for each psychiatric disorder in both case and control groups and also the results of regression analysis for all nine dimensions measured in SCL-90-R Questionnaire are shown in Table 2.