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Figure 1. Rates of home discharge among survivors of critical illness with (black) and without (white) diagnosis of diabetes mellitus, stratified by quartiles of GluSD and corresponding median ICU length of stay. *P = .0007 for trend. Figure 2. Rates of home discharge among medical (black) and surgical Amiloride (white) survivors of critical illness, stratified by quartiles of GluSD and corresponding median ICU length of stay. *P = .0002 for trend. Table 2. Comparison of Rates of Home Discharge and ICU LOSa Across GluSD b Quartiles. Table 3. Comparison of Rates of Home Discharge and ICU LOSa Across GluCV b Quartiles. GluSD was significantly higher among patients discharged home as compared to those who were not, following a similar pattern noted with GV quartiles (Table 4). Mostly similar findings were noted for GluCV (Table 4). Table 4. Comparison of Glucose Variability and ICU LOS Between Patients With and Without Home Discharge. On multivariate logistic regression analysis GluSD was an independent predictor selleck chemicals of a higher rate of home discharge (Table 5) among patients with diabetes, males, and surgical patients. GluCV was an independent predictor of home discharge only among diabetics and surgical patients (Table 5). Increased GV was not associated with an adverse impact on rates of home discharge in any of the examined subgroups or the whole cohort. Table 5. Multivariate Analysis of Glucose Variability as Predictor of Home Discharge Among Survivors of Critical Illness. Among other glycemia-related covariates, only Gluave, the number of hypoglycemic events, and time to achieve the glycemic target following initiation of insulin drip in the ICU were independent predictors buy Ruxolitinib of home discharge in the whole cohort and selected subgroups (Supplementary Tables 1 and 2, available at http://dst.sagepub.com/supplemental). ICU LOS differed significantly across GV quartiles, being shorter in patients with higher GV for the whole cohort and examined subgroups (Figures 1 and ?and2,2, Tables 2 and ?and3),3), except for GluCV among patients with a diagnosis of diabetes. ICU LOS was significantly shorter among patients discharged home (P