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This was based on the assumption of a minimum estimated adherence rate of 25%8 at a 95% confidence interval with 80% statistical power to obtain a sample size of 224. The first patient was randomly selected through a ballot of a set of balls numbered 1 to 5, and the first Selleckchem JQ1 number picked then became the first patient. Beginning from the first patient picked as the starting point on the attendance register for the day every 5th person was selected till the total number of patients required for the sample was selected. The study setting was a 2000 bed tertiary care facility with an average daily out-patient attendance of 1500 and an average admission rate of about 250 patients per day. Type 2 diagnosed patients between the ages of 18 and 75 who visited the medical out-patient department of the hospital were included in the study. Data were collected from May to June, 2011 using a self-administered questionnaire. The questionnaire consisted of respondents�� demographics such as gender, age, levels of education, occupation, marital status, monthly income and mode of payment of diabetic drugs. It also included questions to test their knowledge and beliefs of diabetes mellitus and the use of oral anti-diabetic drugs. The questionnaire was translated into local languages such as Ga, Twi and Ewe and back into English to ensure uniformity without altering the questions to be communicated to the respondents. Adherence level E-64 was determined with the Morisky Medication Adherence Scale (MMAS).9 This is a 4-item inventory used in assessing both unintentional and intentional non-adherence behaviors. Adherence in this study was defined as a ��NO�� response (or a score of 1) to each of the questions on the scale. Four then became the excellent adherence score. However, in this study, binary variables using categorization of 3 or greater versus TAM Receptor inhibitor of the 4 questions of the MMAS was undertaken to determine the direction of their measurement. Logistic regression was performed with statistical significance determined at p