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Exclusion criteria included any lower urinary tract symptoms (LUTS), any urinary tract infection (UTI), any intervention on lower urinary tract, neurological disease (e.g., diabetes mellitus, Thalidomide prolapse intervertebral disc, spinal trauma, etc.) or medications (e.g., anticholinergics, alpha blockers, alpha stimulants, antibiotics, etc) known to affect lower urinary tract function. The participants were asked to fill out IPSS/AUA symptom index and were individually interviewed. Group B: Adult men (>18 years of age) with bothersome voiding type LUTS (poor stream, straining at micturition, sensation of incomplete evacuation, intermittency and hesitancy) irrespective of etiology seen at our clinics were included. The bothersome LUTS was defined as an IPSS score of more than 7 (out of 35) with predominantly voiding type symptoms and global quality of life >2 (out of 6). To maximize size of data, in addition to direct patient-enrollment from urology clinics, department's urodynamic database was also searched from time to time for inclusion of eligible data. It was searched using keywords ��uroflowmetry�� of ��men�� in patient categories ��LUTS,�� ��BPH,�� and ��voiding dysfunction�� during the study period. The participants were asked to report to our urodynamic lab with comfortably full bladder (to normal desire) and void in standing position into gravimetric uroflowmeter (Digital Urodynamic Machine, Solar Silver, MMS International, selleck chemicals llc the Netherlands). Adequate privacy was provided to each participant to minimize psychological inhibition. Data of intermittent flow and of VV?GABA receptors review in urodynamics suite), time to peak flow () and voiding time (TVV) were recorded. In addition, cQmax (=VQImax) and cQave (=VQIave) were calculated using the following equations von Garrelts equations[7] (Eq. 1): VQImax?=?Qmax/; VQIave?=?Qave/. Equations reported in our previous study[3] on men with similar demographic profile as the current study (Eq. 2): VQImax?=?Qmax/; VQIave?=?Qave/. With the idea that the force and velocity of contraction of detrusor corresponds to the ��vis-a-tergo�� strain generated by bladder filling, which corresponds to bladder volume (BV), that is, VV?+?PVR; we used BV instead of VV during assessment of Q�CV relations.