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5?yr (range, 0.8�C18.5?yr). All patients received 10?mg/kg infliximab weekly for 3�C4 doses. Eight patients had CR and two had partial response. None of the patients developed therapy-related adverse effects. All patients developed infections subsequently, which may or may not be related to infliximab. Five ROR1 patients developed chronic GVHD (cGVHD) (four severe, one mild). Six patients died at 66�C1451?days post-transplant, from infection (n?=?3), aGVHD (n?=?1), lung cGVHD (n?=?1), or idiopathic pneumonia (n?=?1). Four patients were alive at 238�C924?days post-transplant, all of whom had an increase in BMI by six?months post-transplant. In conclusion, infliximab is well tolerated and appears effective in children with steroid refractory or dependent GI aGVHD. Infection is common and mortality remains high. ""Schaefer B, Rusai K, Toth A, Pasti K, Ujszaszi A, Kreko M, Horvath E, Sallay P, Reusz GS, Merkely B, Tulassay T, Szabo AJ. Cardiac magnetic resonance imaging in children with chronic kidney disease and renal transplantation. learn more Abstract:? CV disease is the major cause of death in patients with CKD. Recently, CMR imaging emerges as a complementary method providing advantages in cardiac assessment; however, data on CMR in pediatric CKD are scarce. We performed CMR in 15 children: two with CKD, six on peritoneal dialysis, seven on hemodialysis, and in 18 children 5.1 (0.4�C15.4) yr after kidney Tx. Eight children underwent CMR six?months before and after Tx. Results are presented as mean z score?��?SD. LV EF was higher and in the normal range in Tx patients compared with CKD (?0.3?��?1 vs. ?2.1?��?1.6, respectively, p?MK-2206 purchase were lower in Tx children. All parameters improved in the eight children after Tx. In conclusion, our CMR analysis suggests marked improvement of cardiac function and morphology in children after kidney Tx. CMR might be an appropriate complementary method for measuring detailed cardiac status in children with CKD. ""Olaitan OK, Zimmermann JA, Shields WP, Rodriguez-Navas G, Awan A, Mohan P, Little DM, Hickey DP. Long-term outcome of intensive initial immunosuppression protocol in pediatric deceased donor renal transplantation. Pediatr Transplantation 2010: 14: 87�C92. ? 2009 John Wiley & Sons A/S. Abstract:? To report the long-term outcome of deceased donor kidney transplantation in children with emphasis on the use of an intensive initial immunosuppression protocol using R-ATG as antibody induction. Between January 1991 and December 1997, 82 deceased donor kidney transplantations were performed in 75 pediatric recipients. Mean recipient age at transplantation was 12.9?yr and the mean follow-up period was 12.6?yr.
