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A population-based prospective cohort of 65?510 Chinese enrolled from 1998 to 2001 and followed until May 2012. All 18 Elderly Health Service centres in Hong Kong, China. Elderly people aged 65+ years. Self-reported smoking status was assessed at baseline interview and categorized as never, former and current smokers. Compared with never smokers, after adjustment for sex, age, education, social security assistance, housing type, monthly expenditure, alcohol use, depressive symptoms and health status, the hazard ratio (HR) for current smokers was 1.89 [95% confidence interval (CI)?=?1.81�C1.98] for all participants aged 65+ years at baseline, corresponding to an attributable fraction (AF) of about 50%, which is based on AF?=?(HR-1)/HR. Selleck FDA approved Drug Library As the effect of smoking varied with age (P for age interaction Enol All the risk estimates did not vary by sex (P for sex interaction ranged 0.74�C0.89). In Hong Kong, the risk of death from smoking appears to be the same for Chinese women as it is for men. Half of all deaths in Chinese smokers aged 65 years and older and a quarter of all deaths in Chinese smokers aged 85 years and older are caused by smoking-attributable diseases. ""4503" "Telemedicine, care provided by electronic communication, may serve as an alternative or extension to traditional outpatient visits. This pilot study determined the effects of telemedicine on health-care utilization and health status of chronic obstructive pulmonary disease (COPD) patients. One hundred and one patients were randomized, 52 patients received CDK inhibitor telemedicine care and 49 had traditional outpatient visits. The primary outcome was COPD-specific health status, measured with the Clinical COPD Questionnaire (CCQ). Secondary outcomes included St. George's Respiratory Questionnaire (SGRQ) and the Short Form-36 (SF-36) and resource use in primary and secondary care. The mean age of the participants was 68?��?9 years and the mean per cent of predicted forced expiratory volume in 1?s was 40.4?��?12.5. The CCQ total score deteriorated by 0.14?��?0.13 in the telemedicine group, and improved by ?0.03?��?0.14 in the control group (difference 0.17?��?0.19, 95% confidence interval (CI): ?0.21�C0.55, P?=?0.38). The CCQ symptom domain showed a significant and clinically relevant difference in favour of the control group, 0.52?��?0.24 (95% CI: 0.04�C0.10, P?=?0.03). Similar results were found for the SGRQ, whereas results for SF-36 were inconsistent. Patients in the control group had significantly fewer visits to the pulmonologist in comparison to patients in the telemedicine group (P?=?0.05). The same trend, although not significant, was found for exacerbations after 6 months.

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