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001). The mean frictional force of Teflon coated group is statistically significantly lesser than mean frictional force of elastomeric group in the wet state (P Thiazovivin order of frictional force in various groups in dry and wet state. In Table 5, results of paired t-test are shown, which is used to compare mean frictional force in dry and wet state among different groups. It was observed that, the mean frictional force of stainless steel was not statistically significantly different among dry and wet state (P = 0.941). The mean frictional force in the wet state was not statistically significantly different from the dry state in Teflon coated group (P = 0.590). The mean frictional force in dry state was statistically significantly higher than wet state in elastomeric group (P YES1 can occur only when applied forces adequately overcome the friction generated. Various mechanical and biological factors affect frictional properties these factors include archwire properties, i.e. arch wire material and dimensions, bracket to arch wire ligation i.e. type selleck compound of ligation material, and bracket properties, i.e. the bracket slot dimension, the biological properties include saliva and masticatory forces.2 Sliding mechanics is the term usually applied in orthodontics to the controlled movement of teeth along the arch wire. It is hypothesized that, when a slotted bracket is sliding along an arch wire friction impedes movement of the tooth to which the bracket is attached and reduces the force available for tooth movement.3 Ligatures commonly used in orthodontics are either heat treated stainless-steel or elastomeric rings.4 Elastomeric products have been in use in orthodontics since 1960��s as ligatures, continuous chains, etc. Technologically, this is one area that has undergone various studies to prove their existence in the field of orthodontics. These studies have increased the acceptance of these materials in clinical orthodontics.5 Elastomeric ligatures are widely used for engaging the arch wire in the bracket slot due to their ease of application, esthetic appearance, and potential for fluoride release.