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Our partnership with IPOS in 2012 enabled COSA delegates to attend a world class psycho-oncology conference in Australia. We anticipate the UICC collaboration will present opportunities even more vast. As COSA President Elect I am excited about this opportunity and hope to share the experience with you in Melbourne in December 2014. ""Aim:? The use this website of complementary and alternative medicine (CAM) by cancer patients is growing. However, few studies have examined the perceived benefits and adverse effects resulting from the use of CAM by cancer patients. The aim of this study was to evaluate CAM use by cancer patients and to explore their perceptions of the benefit, safety and efficacy of CAM in general. Methods:? Oncologists from three university teaching hospitals screened patients for eligibility. Eligible patients (N?=?1323) were mailed a letter of invitation with a questionnaire between January and May 2008. Results:? Overall 381 questionnaires were returned, showing that 65% of cancer patients used at least one form of CAM. Patients considered taking biological CAM before, during and after chemotherapy. Up to 90% of CAM users believed that CAM provided potential health benefits and less than Ritonavir 3% reported adverse effects experienced from the use of CAM. Most respondents (80%) believed CAM can provide health benefits even when efficacy has not been proven. Most patients (90%) believed that doctors should consider learning about CAM to provide appropriate advice to their cancer patients, and most (83%) indicated they would be happier to accept CAM if it was offered by the hospital. Conclusion:? A substantial portion of Australian cancer patients use CAM. Given the limited data on efficacy and safety for most CAM, it may be reasonable to offer CAM within the hospital environment so its use can be monitored and patients can receive more evidence-based care. ""CD44v6 is an isoform of CD44 that can be present in soluble form (sCD44v6). The aim of this study is to evaluate the presence of soluble CD44 (sCD44) and sCD44v6 in serum of children with B-cell precursor acute lymphoblastic leukemia (B-ALL) and their relationship with prognosis. sCD44v6 and sCD44 levels were measured in the sera of patients and healthy Dabrafenib order children by enzyme-linked immunosorbent assay. The level of the molecules was analyzed in relation to laboratory and clinical characteristics of the patients at presentation and response to therapy. sCD44v6 was significantly lower in patients (103.4?��?44?ng/mL) than in controls (173.5?��?73.6?ng/mL) whereas the serum level of sCD44 showed no significant difference between the groups. In patients, sCD44v6 quantity was inversely correlated with sCD44 level (r?=??0.57, P?