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Chest radiograph revealed subpleural assymmetrical fibrosis, nodules and areas of bronchiectasis bilaterally. A HRCT showed ill defined nodules, patchy consolidations and areas of bronchiectasis involving bilaterally and tree in bud appearance in peripheral part of the lower zones in both lungsand patchy ground glass opacities. An open lung biopsy showed collections of inflammatory cells and lymphoid cells around the bronchioles, consistant with diffuse panbronchiolitis. PFI-2 purchase A diagnosis of diffuse panbronchiolitis was made according to the clinical radiological and histolgical evidence. He was started on a prolonged course of oral corticosteroids, 0.5?mg/kg/BW, toghther with azithromycin 250?mg bd. At three months of follow up patient showed significant clinical improvement and flupentixol continues to be regulary followed up at the clinic. Discussion:?DPB can mimic common disorders like bronchial asthma, tuberculosis and other chronic lung infections. However if diagnosed early, it can be treated with a significant improvement and good prognosis. The detection of a case of DPB which is rare in this region emphasizes the importance of maintaining the clinical suspicion and doing the relevant investigations in order to make a diagnosis in the appropriate clinical setting. SAMUEL HALIM1, ZULKIFLI AMIN2 1Department of Internal Medicine, School of Medicine, University of Tarumanagara, Jakarta, Indonesia, 2Division of Pulmonology, Department of Internal Medicine, School of Medicine, Universitas Indonesia, Jakarta, Indonesia Background:?Mortality Duvelisib due to Hospital Acquired Pneumonia (HAP) is high, in certain part of the world it may reach up to 50% and currently Indonesian data showed similar proportion. As far as our concern, there are too few published studies about the mortality and predictors of mortality in Indonesian HAP patients. These data are important to improve the management of HAP in order to decrease mortality. Objectives:?The aims of this study were to identify predictors of in-hospital mortality in HAP patients and develope a scoring system as a prediction model of mortality. Methods:?This was a retrospective cohort study. Subject's data were taken from medical records from January 2006 to December 2012 of Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia. Independent variables consisted of age over 60, decrease of consciousness, shock, sepsis, hypoalbuminemia less than 3 g/dL, immune-compromised, late onset HAP. We used logistic regression test, with backward LR method for multivariate analysis. We developed the scoring system by analysing the area under the receiver operating curve (AUROC) and the Hosmer-Lemeshow test. Results:?There was 204 HAP patients included with all completed data. The mortality proportion of our HAP patients was 44.1%. Multivariate analysis showed that the predictors of mortality in patients with HAP were decrease of consciousness (p?
