Marketing Report - R428 Considered An Absolute Must Nowadays

The interaction of time and study condition will be of primary interest in each analysis, with a significant interaction indicating a group difference in the pattern of change over time in the outcome of interest. Significant interactions will be explored using sets of Bonferroni adjusted comparisons of the two groups at post-intervention and 3-month follow-up. All effects will be tested at PE-64 in reducing the substantial unmet need for psychosocial care in young people with type 1 diabetes R428 in vivo [6,15]. To our knowledge, this study will be the first to examine the effectiveness of a fully-automated, self-help intervention that is generic in its content and delivered via the Internet to computers, tablets, and mobile phones for reducing mental health symptoms and improving mental well-being in this vulnerable patient group. myCompass is a public health intervention of demonstrated efficacy [25]. We hypothesize that general and diabetes-specific distress and psychological well-being will improve significantly in young people randomized to myCompass for 7 weeks compared to those randomized to an active placebo intervention. Intervening to reduce psychological distress in young people with type 1 diabetes is important as emotional difficulties are associated with poorer self-care and high disease-related morbidity and mortality [9-11]. Furthermore, in the absence of treatment, psychological distress during the transition from childhood to adulthood may persist throughout life, thereby substantially increasing the longer-term personal and societal burden of the disease [12]. The preferred communication media of young people [52], delivering mental health care via the Internet and mobile phones find more may be particularly attractive to many young patients who are reluctant to access traditional face-to-face supports. Moreover, if found to be effective, myCompass is broadly available free of charge and could potentially reach large numbers of young people with type 1 diabetes for whom service availability and cost are major barriers to access. Previous studies of psychological interventions for people with diabetes have tended to focus on depressive symptoms and diabetes-specific outcomes (eg, diabetes-related distress and diabetes self-care).