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For most demographic variables (Table 1), no substantial differences were observed across the total sample for key variables (e.g., percentage of respondents who used oral vs. insulin treatment or had type 1 vs. type 2 diabetes). Significant cross-country differences, however, were found for age (ANOVA, P Paclitaxel in vitro mean age (37.6 �� 12.3). The greatest percentage of females was found in the United States (64.1%), whereas Germany had the smallest proportion of females (42.8%). The mean duration of diabetes was longest in the US (15.8 years, SD 12.7) and shortest in Germany (8.5 years, SD 7.7). Fifty-one percent of individuals with type 1 diabetes (range: 43.3% in Germany, 64.5% in the United States, P Fluconazole recent NSHE, 34.0% of respondents reported that the event occurred at work, 48.9% indicated during the day, but not at work, and 16.6% reported during sleep at night. Most documented NSHEs (?��60%) were symptomatic and confirmed by a blood glucose test. The majority of respondents (94.8%) identified their NSHE through hypoglycemic symptoms (confirmed or unconfirmed by blood glucose test). A small proportion (range 12.5%�C17.1%) had no symptoms, but identified their NSHE solely using blood glucose testing. The percent of asymptomatic events per country were: United selleck kinase inhibitor States �C 16.9%, United Kingdom �C 12.5%, Germany �C 12.7%, and France �C 17.1%. The primary self-reported causes for NSHEs were irregular or insufficient food intake or diet (48.2%), physical exercise or overexertion (34.1%), and/or stress (32.0%). Among respondents who reported intentionally trying to lower their blood glucose levels as causative, a miscalculated insulin dose (16.7%) or general poor control (11.4%) were the most commonly reported events. Respondents reported that their NSHEs lasted an average of 33.0 minutes (SD 60.6). As shown in Table 2, across all respondents the predominant strategy for managing the most recent NSHE was the use of sugar drinks and packs. Approximately one-third of the total sample (range 25% Germany to 43% United States) also ate a meal to deal with their event.