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1 to 1.4 during the study period (data not shown). Time trends of AOH and very preterm delivery The prevalence of very preterm delivery per 100 pregnancies was 1.5% in the study population (9,157/617,906), whereas the rate of very preterm delivery after AOH per 100 pregnancies was 0.6% (3,922/617,906) (Table 2). These prevalences remained relatively constant during the study period. In pregnancies with AOH, the prevalence of very preterm delivery increased from 6.9% to 9.2% (Table 2). Of the overall very preterm deliveries, more than one-third occurred in pregnancies with AOH, and the proportion increased from 40% to 44% during the study period (Table 2). The very preterm delivery and perinatal outcomes as results of pregnancies with AOH are summarized in Table 2. Diagnostic categories for AOH The diagnostic categories for AOH are shown in Dipivefrine Figure 2. Sixty-seven percent of the overall AOHs were registered by diagnoses in only one diagnostic category (data not shown). Figure 2 Main diagnostic categories of AOH in Denmark 2003�C2012. The five most frequent diagnostics categories associated with AOH during the study period were threatened preterm delivery, maternal diseases, molimina, delivery, edema, proteinuria, and hypertensive disorders (Figure 2). All diagnostic categories showed a decline except maternal diseases, CX-5461 in vitro which increased by 145%, from 660 hospitalizations in 2003 to 1,616 in 2012 (Figure 2). The most frequent diagnostic category was threatened preterm delivery, explaining the 15% (318/2,048) decrease in AOH during the study period (Figure 2). Of all the pregnancies, 2.6% (15,823/617,906) had a history of AOH within the diagnostic category ��threatened preterm�� delivery. Of these pregnancies, 14.9% (2,363/15,823) resulted in a very preterm delivery (data not shown). The overall rate of the selected subdiagnoses in the threatened preterm delivery diagnostic category Forskolin mw decreased by 16%, from 1,779 at the start of the study to 1,499 at the end of the study. The threatened preterm birth and the preterm prelabor rupture of membranes subdiagnoses decreased, whereas the diagnoses of clinical cervical incompetence, ultrasonic cervical incompetence, and contractions at