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20121a011160 and No. 20131a011157). MYUNG-GOO LEE1,2, CHANG YUL LEE1,2, SOON JONG YU3 1Division of Pulmonary, Allergy & Critical Care Medicine, Hallym University Chuncheon Sacred Heart Hospital, Republic of Korea, 2Lung Research Institute of Hallym University College of Medicine, Republic of Korea, 3Infection Control Team, Hallym University Chuncheon Sacred Heart Hospital, Republic of Korea Purpose:?This study was designed for analyzing secular trends of incidence and clinical characteristics for ventilator-associated pneumonia (VAP) Selleckchem Pazopanib in the intensive care unit (ICU) at one university hospital. Methods:?Study population was 97 patients who were diagnosed as VAP at ICU from 2007 to 2012. VAP incidence use discharge patients, patient-days, and ventilator-days as each denomnator. We compared VAP rates by Poisson regression. ICU inpatients' and VAP patients' characteristics were analyzed by descriptive statistics. Results 1)? Mean age was 59.36?+/??17.34 and male was 74(76.3%). Common initial diagnoses were cerebrovascular and neurologic diseases (37.1%) followed by cardiovascular diseases (20.6%). Conclusion:?The annual incidence of VAP was decreasing, which could be explained by active surveillance and infection control measures. JEONG HA MOK, SANG HEE LEE, JUNG SUP EOM, EUN JUNG CHO, MI HYUN KIM, KWANGHA LEE, KI UK KIM, HYE-KYUNG PARK, MIN KI LEE Department of Internal Medicine, Pusan National University Hospital, Busan, Korea Background:?Rapid pathogen identification and appropriate antibiotics therapy is important to treat critically ill patients. This study was conducted to evaluate the usefulness of Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass spectrometry http://www.selleckchem.com/products/BAY-73-4506.html (MALDI-TOF MS) for rapid pathogen identification for critically ill patients with pneumonia. Methods:?We conducted a retrospective study in the intensive care unit (ICU) at Pusan National University Hospital in Korea from May 2012 to February 2014. Patients who performed microbial culture and organism identification of endotracheal aspirate while receiving ventilator care were enrolled. Results:?A total 50 patients were included final analysis. Pathogen identification was performed using MALDI-TOF MS in 27 patients (MS group) and conventional methods in 23 patients (Conventional group). There ALK were no differences in demographic characteristics and disease severity between two groups. When comparing two groups, the average time between endotracheal aspirate sample collection and pathogen identification (with antibiotics susceptibility test result) was shorter in MS group than conventional group (51.9?��?10.8?hr vs. 70.5?��?28.2?hr, p?
