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The correlation of the AE-QoL total score and the SF-36 ��Mental Component Summary�� was particularly high (r?=??0.68, P?selleck chemicals ��mild�� to ��severe��. However, no sufficient discriminative ability was seen between the categories ��none�� and ��mild�� as well as ��severe�� and ��very severe��. The AE-QoL domain scores and the AE-QoL total score were compared in a subsample of 46 patients who completed the questionnaire twice in an interval of three weeks (Table?8). No meaningful differences could be detected. The interclass correlation coefficients were?>?0.70 for ��Functioning��, ��Fears/Shame��, ��Food�� as well as for the AE-QoL total score, indicating good reproducibility. Only the coefficient for ��Sleep/Mood�� was slightly lower (r?=?0.68). Multiple linear regression analysis was performed to identify Cilengitide drivers of QoL impairment in angioedema patients. This revealed find more that gender (P?