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The aim of this prospective study was to analyze the results of the initial experience. Materials and Methods From October 2013 to December 2014, 97 consecutive patients, median age 3.6?years (range 27?days to 52?years), with median body weight 12.1?kg (range 800?g to 62?kg), underwent surgery for pediatric and congenital heart defects in our new unit. Criteria for exclusion from this study were operation performed without the use of CPB or operation performed with the use of even a mild degree of hypothermia Talazoparib molecular weight (Dabrafenib purchase high flow CPB and were prospectively included in the study. Forty-two patients (42/97?=?43%) were excluded from the study because they were operated on either without CPB (40 patients) or because the operation required CPB with a period of hypothermia (binedaline Table 2 List of surgical procedures. The Basic and Comprehensive Aristotle Score (10) were used to assess the potential mortality and morbidity in our patient population. Data collection All database regarding patients operated with normothermic CPB were prospectively recorded. The overall outcomes of the operation included: survival, need for re-operation, ICU, and hospital stays. Intra-operative data included duration of CPB and aortic cross-clamp, need for inotropic support, lactate level, and urine output. Post-operative data included duration of mechanical ventilation, and type, dosage and duration of inotropic support; in addition lactate level, urine output, and chest drains bleeding were recorded on arrival to ICU, after 3 and 6?h, and at 8:00 a.m.