Representative records showing the difference in maximal transport rate of the Ca2 pump (PVmax) from the declining phase of the Ca2 -transient following the KCl- induced depolarization

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A considerably larger [Ca2+]i could be calculated twenty and 40 seconds right after the commencing of KCl application (112 nM, and a hundred and ten in handle, whilst a hundred and fifty nM and 135 in cloneC1 cells, respectively) indicating a decreased Ca2+-uptake capability of the SERCA pumps (Fig 4C). This was further quantified by extracting PVmax(maximal transportation fee of the pump see Resources and We found that the deletion mutants DFgABC3 and DFgABC4 had obtained a larger sensitivity to numerous fungicides belonging to the SBI class strategies), which was evidently diminished (p