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The least and most scores, in any dimension, were 0 and 100, respectively. This questionnaire has been prepared and compiled through the cooperation of 15 international departments in order to be used in different cultures.15 In addition; its validity has been approved in the study performed by Yousefy et al. in Iran.16 The Coopersmith Self-esteem Inventory (CSEI) YES1 was applied to study patients' self-esteem level. This inventory is one of the most famous instruments in measuring self-esteem and has been used frequently. This scale consists of 58 questions 26 of which were related to general, social, familial, and professional issues. In addition, 8 questions were specified for fake replies which, in fact, are considered as a sign of a defensive reaction toward the questionnaire. Therefore, the lowest and highest scores are 0 and 50, respectively. The closer the score is to 50, the higher the level of self-esteem and vice versa. The test-retest reliability coefficients of the CSEI have been respectively reported as 0.91 and 0.73. The validity and constancy of this instrument has been found to be 92% in previous research which reflects the constancy, reproducibility, and accuracy of this instrument.17 Delaram et al. calculated the validity of the CSEI by test-retest Selleck Thiazovivin method at 90% and 93%, respectively.18 Data were analyzed by descriptive-analytical statistics and using SPSS for Windows (version 15; SPSS Inc., Chicago, IL, USA). Chi-square test was used to compare the relationship between self-esteem and quality of life in patients with ITP. Results The results showed that 32% of patients were 36 and older, 59% were female and 26.6% had primary education. The majority of ITP patients (29.7%) had low self-esteem and quality of life. Chi-square test showed a significant relationship between self-esteem and quality of life of ITP patients (p = 0.03) (Table 1). Pearson��s correlation coefficient showed no significant relationship between mean Icotinib in vitro total score of self-esteem of patients and their demographic variables (age, hospitalization frequency). However, it showed a significant relationship between self-esteem and duration of illness (r = 0.26, p

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