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A hypothesis assuming that an average increase in quality of life in both groups is essential, i.e. indeed differs from zero, was also verified. For that purpose a parametric t-Student test was applied for dependent groups. Results shown in Table 1 show that an average increase in both groups is positive and indeed differs from zero. It means that in both groups, a significant improvement in quality of life took place after immunotherapy. Table 1 Average increase in quality of life of patients with asthma and allergic rhinitis In order to compare average increases in quality of life, z-test based on normal distribution was applied. According to the central border statement, the use of this CAL-101 concentration test was justified because of large numbers of compared groups. The test showed significant differences. The value of calculated z-statistics was 3.45 and is greater than 1.96 critical value taken from the table of normal distribution (p Sitaxentan assessed. Statistical analysis of data obtained from examinations was conducted in order to compare quality of life before implementation and after completion of immunotherapeutic treatment. Cases of increase and decrease in quality of life in the group of patients with asthma and allergic rhinitis were counted. A hypothesis was verified that changes in quality of life in each research group differed significantly. For that purpose a test was applied for two fractions (test for two rates of the structure). Results of calculations and tests are shown below. Increase in quality of life which was established on the basis of a great number of answers received as a result of the survey was regarded as objective. Respondents simultaneously answered a question about how much quality of life changed after immunotherapy by marking one of 5 replies on a scale from 0 (did not change at all) to 4 (to a high degree). Such evaluation can be considered as subjective. On Afatinib the basis of results it was established whether there is any correlation between objective and subjective assessment of quality of life of patients. For that purpose, Pearson's correlation coefficients were calculated and verified (Table 3). Table 3 Correlations between objective and subjective assessment of quality of life Another stage is an attempt to find a possible correlation between increase in objective quality of life and subjective evaluation of quality of life done by the patient. This procedure was performed in order to find out whether there is any relationship between the objectively assessed increase in quality of life and subjective evaluation.
