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To assure the curve fitting parameters represent the measured force redevelopment data accurately, trials that could not be fitted with a quality of R??>?0.96 (n?=?4) were not used for statistics. For further analysis, parameters of equation?1 were pooled find more according to pure shortening and stretch-shortening trials. Figure 3 Typical data (n?=?1, filtered with lowpass 10?Hz) of force redevelopment after pure shortening (SHO-30, SHO-20, SHO-10) and stretch-shortening (SSC-30/30, SSC-30/20, SSC-30/10) contractions and corresponding double exponential ... Statistical analysis Data were tested for normality (Kolmogorov�CSmirnov test) and either repeated measures ANOVA (or nonparametric Friedman tests) with Bonferroni�CHolm post hoc comparisons (Students t-tests or Wilcoxon test) were used to identify significant differences between parameters of mean force, work and parameters of force redevelopment after pure shortening and stretch-shortening, as well as for comparisons of forces to the corresponding purely isometric reference contractions. Statistical significance was set at P?DDR1 exceeding the respective mean by more than �� 2SD, were excluded from statistical analysis. Results Baseline The mean electrically evoked tetanic isometric peak force at 20�� was 52.1?��?9.6N, representing 50.0?��?5.7% of the initial force achieved during MVCs (104.4?��?15.6N). Peak force, minimum force and work Peak forces at the end of the stretch phase for ��STR-30�� were significantly greater (89.0?��?12.0N; P?Selleck Temozolomide (Table?(Table1).1). In addition, this ��STR-30�� peak force was not statistically different (P?=?0.432) to peak forces at the end of the stretch phase in all stretch-shortening tests (91.5?��?13.7N, 91.4?��?13.0N and 89.1?��?13.7N for SSC-30/30, SSC-30/20 and SSC-30/10, respectively). Work during shortening was significantly (P?