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9%) were pre-diabetic whereas 20 (10.8%) were pre-hypertensive. Five (2.7%) GPCR Compound Library subjects had both pre-diabetes and pre-hypertension. Among the pre-hypertensives, 25% also had pre-diabetes (Table ?(Table2).2). However among the pre-diabetics, 8.2% had pre-hypertension. Table 2 Co-prevalence of diabetes and hypertension The correlation of systolic blood pressure with fasting plasma glucose was not found to be statistically significant. However, the correlation of diastolic blood pressure with fasting plasma glucose was significant (P 21.8 �� Ribonuclease T1 3.0 kg/m2 and the association was found to be significant (Table ?(Table4).4). There was no significant association between the waist circumference, systolic blood pressure and serum HDL of normoglycemic and pre-diabetic subjects. However, the mean diastolic blood pressure of pre-diabetics (82 �� 5 mmHg) was significantly higher than normoglycemics (79 �� 6 mmHg). Mean serum cholesterol, serum triglycerides, and serum VLDL was also higher among pre-diabetic subjects as compared to normoglycemic subjects and the association was found to be significant. Mean serum LDL was also significantly higher in prediabetics (104.1 �� 22.7 mg/dL) than in normoglycemics (92.7 �� 23.6 mg/dL). Table 4 Determinants of impaired fasting plasma glucose Multiple linear regression analysis for the determinants of fasting plasma glucose was done and the adjusted R2 was 23.5% (Table ?(Table5).5). Waist circumference, systolic blood pressure, serum cholesterol, serum 4Methylumbelliferone triglycerides, serum HDL, serum VLDL were not significantly associated with fasting plasma glucose. For every 1 mmHg increase in diastolic blood pressure, the fasting plasma glucose was expected to rise by 0.375 mg/dL (�� = 0.375) and this association was found to be significant (P