The Eleven MostOver The Top FKBP Tricks... And Ways To Utilise Them

One hundred eighty-seven eyes of 187 glaucoma patients (mean follow up 6.92?��?1.67 years) being treated with topical antiglaucoma medications (at least 3 years) with no history of surgery or laser were included and compared with 100 eyes of 100 age�Cmatched, untreated control subjects (mean follow up 6.58?��?1.93 years) who were glaucoma suspects with normal intraocular pressure not on any treatment. Demographic data, central corneal thickness and intraocular pressure were collected at initial glaucoma diagnosis and at most recent visit, and findings were compared between two groups. Mean change in central corneal thickness in microns (��m). Central corneal thickness fell significantly (P?SRT1720 in vitro eyes and 1.17?��?8.75?��m in controls. Among treated eyes, central corneal thickness reduction was significant (P?FKBP reduction occurred in eyes treated with only beta-blockers (P?=?0.15) when compared with control eyes. Prostaglandins appear to be associated with a small but significant central corneal thickness reduction over time. Serial central corneal thickness measurements might be helpful in glaucoma patients, particularly those on prostaglandins. ""The water-drinking test has been used as a stress test to evaluate the drainage system of the eye. However, in order to be clinically applicable,a test must provide reproducible results with consistent measurements. This study was performed to verify the reproducibility of intraocular pressure peaks and fluctuation detected during the water-drinking test in patients with ocular hypertension and open-angle glaucoma. A prospective analysis of patients in a tertiary care unit for glaucoma treatment. Twenty-four find more ocular hypertension and 64 open-angle glaucoma patients not under treatment. The water-drinking test was performed in 2 consecutive days by the same examiners in patients not under treatment. Reproducibility was assessed using the intraclass correlation coefficient. Peak and fluctuation of intraocular pressure obtained with the water-drinking test were analysed for reproducibility. Eighty-eight eyes from 24 ocular hypertension and 64 open-angle glaucoma patients not under treatment were evaluated. Test and retest intraocular pressure peak values were 28.38?��?4.64 and 28.38?��?4.56?mmHg, respectively (P?=?1.00). Test and retest intraocular pressure fluctuation values were 5.75?��?3.9 and 4.99?��?2.7?mmHg, respectively (P?=?0.06). Based on intraclass coefficient, reproducibility was excellent for peak intraocular pressure (intraclass correlation coefficient?=?0.79) and fair for intraocular pressure fluctuation (intraclass correlation coefficient?=?0.37).