The Most Significant Belief Regarding C59 Shown

The final evaluation for short term toxicity took place one month after the last insertion. Statistics Mean values, standard deviations, and standard error of mean were calculated from 32 TO and 20 TR applications. Because we could not assume whether TO or TR values would be larger or smaller, two tail t test was utilized to calculate p-value. Results All patients received four fractions of HDR brachytherapy for a total of 52 treatments (32 TO and 20 TR). Dosimetric results of the 52 applications and CT-based plans are presented in Table 1. Of the measured parameters, the dose to the right point B was significantly different between TO and TR. The mean dose to the right point B was higher in TO than TR. Although the rectal D2cc were statistically similar Aldosterone between TO and TR, the mean rectal C59 molecular weight dose in TR was lower than TO. Given that the primary optimization goal was to deliver the prescription dose to points A, dosimetric results were similar for most parameters between the two applicators. Optimization goals were made to achieve GEC ESTRO dose constraints to bladder, rectum, and sigmoid colon. Hence, doses were intentionally minimized to the OAR contoured, resulting in no statistical differences seen in the dose to points A, the D2cc rectum, the mean dose, and D2cc bladder, or the mean dose and D2cc sigmoid. Table 1 Dosimetric parameters for tandem and ovoids (TO) and tandem and ring (TR) applicators Treatment volumes and durations are presented in Table 2. V95%, V85%, V50%, and V20% were all significantly higher for TO than for TR (p the two applicators. The total treatment time was significantly longer for TO vs TR applicators (p MLN8237 research buy (CTV100%) and the percent of prescription dose covering 90% of the CTV (D90) were not statistically different between TO and TR applicators. For dose distributions in regards to TO applicators, the above dosimetric parameters are described for applicators using small ovoids. Table 2 Volumes of all tissues that received various doses, target volume receiving prescription dose, total duration of treatment, and acute toxicities for tandem and ovoids (TO) and tandem and ring (TR) treatments Clinically, there were no statistical differences in the RTOG acute �� grade 2 GI or �� grade 2 GU toxicities seen between TO and TR (Table 2). Two patients in the TO group experienced acute �� grade 2 GI toxicity, whereas one patient in the TR group experienced acute �� grade 2 GI toxicity. No vaginal fibrosis or stenosis was detected in either group during short term follow up.