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Ultimately, I am not sure whether any of these things would have made a difference. I think that people who have never really failed in any other area have an incredibly hard time believing that they cannot succeed in moderating their drinking. Perhaps it simply comes down to the need to hit bottom before recovery can begin. Nevertheless, widely disseminated research-based information may prevent or raise that bottom for some at-risk drinkers, and that is reason enough to do this work. A: Your husband was the founder and president of a microbrewery. Would you be willing to comment on how this may have affected your work? DD: I should first mention that the microbrewery was a second career for my husband. At the time we married, we were both involved in population research, his based on evaluating international BMS-777607 price family planning programs. (Later, after he started giving tours at the brewery, he joked that he had had the perfect set of careers��sex and alcohol. Now that I think about it, one could say the same of my career.) Jerry left his Federal government job and started the brewery just a few months before I accepted my job at NIAAA, and I am grateful that neither Bridget Grant nor Enoch Gordis, Director of NIAAA at the time, considered this to be a factor that would preclude my being hired. To avoid any perceptions RVX-208 of conflict of interest selleck kinase inhibitor in my work, I have avoided research about specific alcohol policies and research on benefits of drinking and beverage-specific effects of drinking. I do not think my husband's occupation in the craft brewing industry (which ended 3 years ago when he sold the brewery) was in any way analogous to receiving research funding from the alcohol industry. I once argued that I did not think it was any different from his owning a restaurant where alcohol was served, or a grocery store that sold beer and wine. At the same time, I should acknowledge that his activities gave me a less monolithic view of the alcohol industry than that of most alcohol researchers and a perspective more sympathetic to the economic forces that make it difficult for small craft producers of alcohol to survive. Within my experience of this small and admittedly unrepresentative sector of the beverage industry, economic survival and strategic planning were always described in terms of gaining a larger market share rather than in terms of expanding the market; in fact, the brewery motto was ��Don't drink more, drink better��. Consequently, I tend not to see the industry in quite such adversarial terms as do many researchers.