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Continuous variables are expressed as medians and interquartile ranges, and categorical variables as frequencies and percentages. Nonparametric tests were used to compare distributions (chi-square test or Fisher��s exact test for categorical variables; and Student��s t-test, after log transformation if necessary). p Sunitinib Atlanta, GA, USA). The 221 S.?aureus infections were community-acquired in 38% of cases (n?=?84) and hospital-acquired in 62% of cases (n?=?137). The most frequent diagnoses were skin and soft-tissue infections (75% and 69.4%, respectively, of community and hospital infections), bone and joint infections (9.5% and 12.4%), bacteraemia (3.5% and 8.7%), pneumonia (6% and 4.4%) and others (6.0% and 5.1%); none of these differences was statistically significant. Most community infections were diagnosed in the emergency room or during outpatient visits (53.6%) or in medical wards (36.9%), whereas most hospital infections were diagnosed in medical (65%) or surgical (20.4%) wards (data not shown). MRSA accounted for 40.5% (n?=?34) of the 84 community infections and for 47.4% (n?=?65) of the 137 hospital infections (no significant difference, table?1). Patients with C-MRSA infections were significantly younger than patients with hospital MRSA infections. Skin and Selleck 3-Methyladenine soft-tissue infections were significantly Ceftiofur more frequent among patients with C-MRSA than among patients with C-MSSA (p?