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05); 17 (89.5%) children with 10 or more MN were exposed to the sun for more than 14?days, SERCA versus 2 (10.5%) children with 10 or more MN who had a summer holiday of only a few days. There was no correlation between the frequency of sunscreen use and MN counts. Sunburns were not statistically significantly associated with more MN (p?=?0.32); the mean number of MN found in children with a past history of sunburns was 6,019, compared with a mean of 5,678 reported in children without. There was no loss to follow-up, and all 144 children were reexamined after 1?year. The total number of MN observed was 954; 118 new MN were identified in 66 (45.8%) children (Table?4), 57 of whom were of phototype III and 9 of phototype II (mean of new MN found in children with phototype II, 0.47?��?0.9 and phototype III, 1?��?1.15). The mean number of preexisting MN in the 66 children who developed new MN after 1?year of follow-up was 5.4, which was comparable with the mean number of MN in the total study population (5.8); there was no correlation between the number of preexisting MN and new MN. The trunk and neck area was the most common region involved in the appearance of new MN (n?=?68, 57.6% of all new MN) (p?www.selleckchem.com/products/ON-01910.html observed in new MN was globular (49.1% of all new MN, n?=?58). Seventy-two new MN were found in children with a past history of sunburns, versus 46 Wortmannin in those without (p?=?0.27). Despite this, the number of new MN was significantly higher in children who reported sunbathing in the summer for 14 to 28?days (60 new MN) than in those reporting 7?days or less (24 new MN) (p?