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A systematic electronic literature search was conducted to identify RCTs comparing the use of Carisolv with a control (rotary instruments) in patients with dental caries. Results were expressed as risk ratios (RRs) or mean differences with accompanying 95% confidence intervals (CIs). The outcome measurement included the complete caries removal rate (CCR: the number of cases with complete caries removal in study and control groups after different treatment), the treatment time (min) and the use of local anaesthesia. The meta-analysis was performed with the fixed-effect or random-effect model according to the heterogeneity. Six studies involving 578 teeth met our inclusion criteria. There was no statistically significant difference in CCR between Carisolv group and rotary instruments group; in Carisolv group, the treatment Tenofovir ic50 time (min) was significantly longer no matter whether the caries was located in coronal or root area, while the use of local anaesthesia was less. Compared with rotary instruments, Carisolv did not show increased CCR. Carisolv reduced the use of local anaesthesia although it took longer treatment time. However, the results should be interpreted cautiously due to the heterogeneity among study designs. Further large-scale, well-designed RCTs are needed. ""The aim of this study was to examine the effect of mouth breathing on masticatory muscle activity during chewing food. Masseter muscle activity tuclazepam during chewing of a rice ball was recorded in 45 adult volunteers (three women), identified as nose breathers. Surface electrodes were placed beta-catenin inhibitor on the skin according to the orientation of the masseter muscle to record the activity of this muscle while the subjects chewed the food until swallowing. Each activity was recorded twice, once with nose breathing and once with mouth breathing induced by nasal obstruction. The integrated and mean electromyography values for mouth breathing were significantly lower than the values for nose breathing (P?
