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3 �� 19.99 mL3. These selleckchem results showed clearly that LV volume was less than normal in most of our patients. Statistical analysis showed that there was a significant difference between LVEDV measured by RT3DE in the studied TOF patients and that of control group (p diglyceride images. Secondly, the transducer IOX1 supplier was positioned in only an apical acoustic window. Technically, to acquire a RT3DE data set, the whole LV cavity could not always be placed within the image angle.9) Also this is near to the study done by Heusch et al.14) who denoted that LVEDV measured by RT3DE was smaller than those calculated from the angiocardiography but the correlation between the two methods is good (r = 0.93, p = 0.0001). The above data clearly illustrates that RT3DE can be used as a reliable method for accurate estimation of left heart volume in children. 2D echocardiography alone cannot be used for assessment of the LV volume because 2D echocardiography measures single ventricular dimension rather than a ventricular volume. This dimension can give a good impression of cavity size but less accurate for precise quantification of LV volume.15) In our study, LVEF measured by RT3DE was significantly underestimated in comparison to that measured by 2D echocardiography, which suggested that RT3DE underestimate EF when compared to 2D echocardiography. This was also reported by other investigators. The reason for this underestimation may be that RT3DE cannot consistently differentiate between the myocardium and the trabeculae.