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Fig. 4. The escalating effects of the number of missed or shortened dialysis treatments in the previous month on age-adjusted hospitalization rates. Discussion The main observations from Quisinostat mw this study are that missed and shortened dialysis treatments are more prevalent among the minority populations (AA, Hispanic and NA patients), younger patients aged ankyrin to be a nationwide phenomenon that defies logical explanations. Since non-adherence is more prevalent in younger patients, such patients may feel they are physically healthier than the older patients and thus can ��get away�� with missed treatments [11]. It has also been suggested that a missed or shortened treatment may represent a subtle expression of control over their health status [12]. Other factors that have been associated with a high frequency of non-adherence are: smoking [5, 6, 9, GSK-3 inhibitor 13]; use of illicit drugs and substances [9, 13]; poor adjustment to the diagnosis of ESRD and the dialysis treatment [14]; poor perception of satisfaction with the nephrologist [15]; and depression and psychosocial problems [16, 17]. The impact of psychosocial problems in ESRD has not been fully investigated. It has been reported that almost 10% of a prevalent cohort of US-HD patients were hospitalized with a psychiatric diagnosis over a 1-year observation period [18]. Our study was not designed to evaluate these issues, but ESRD providers should be cognizant of such issues. The retrospective design of this study did not allow for an accurate record of the specific reasons for the missed or shortened dialysis treatments.