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Patients with history of spinal disease conditions (confirmed through clinical and radiological findings) like disc bulge, disc prolapse, Kypho-scoliosis and patients with lumbar spinal fractures following trauma were excluded. Institutional ethical clearance was obtained, letter dated 14-11-2011. The scanned images were viewed using DICOM viewer and the following dimensions were measured. The Vertebral Body Diameter (VBD) measured between the anterior and posterior border at the middle of each vertebral body of L1 to L5 lumbar vertebrae on T2 sagittal section MRI of lumbar spine. The Dural Sac Diameter (DSD) measured between the posterior wall of the vertebral body to the anterior border of the Metabolism inhibitor spinous process on the T2 sagittal section MRI of lumbar spine at L1 to L5 [8] [Table/Fig-1] The Canal Body Ratio (CBR) calculated by dividing the DSD by the VBD. In a study by Mohammed el Rakhwey a similar canal body ratio was measured on dry bones by measuring the interpedicular distance to calculate the vertebral foramen diameter [9]. [Table/Fig-1]: Comparison of the Vertebral Body Diameter in males & females (n=154) The cross-sectional area containing the dural sac is measured through the midpoint of the posterior border of the disc and ligament flavum on each side on T2 axial section of MRI lumbar spine at L1 to L5 lumbar vertebral levels. The area can be measured manually by RhoC using pencil tool to calculate area through the DICOM image computer software. The cross sectional area of the lumbar vertebral body on T2 axial section of MRI lumbar spine of the first to the fifth lumbar vertebral bodies on T2 axial section of MRI lumbar spine at L1 to L5 lumbar vertebral levels. The area was measured as GSK1210151A datasheet depicted above [Table/Fig-2] [10]. The ratio of the dural sac cross sectional area to the vertebral body cross sectional area of the lumbar vertebrae L1 to L5 was calculated. Calculation of this ratio as a criteria to predict the occurrence of canal stenosis was a new method that was performed in our study. [Table/Fig-2]: Comparison of the Dural Sac Diameter in males & females at all lumbar vertebral levels (n=154) Statistical Analysis The data collected was tabulated and computer based statistical analysis was done using SPSS software. The students unpaired t-test was employed for statistical analysis. Results The Mean Diameter of the Lumbar Vertebral Body showed a gradual increase in size craniocaudally from the first to the fifth lumbar vertebral levels, while, the Mean Dural Sac Diameter showed a craniocaudal decrease in size [Table/Fig-3, ?,4].4]. The difference in the mean vertebral body diameter between males and females was found to be extremely significant with p-value