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23 We assumed that 30% of the control subjects were exposed to any risk factor and defined the significance level at 0.05. Our sample could provide a statistical power of 80% to detect a minimum OR of 2.0. Statistical analyses First, a descriptive analysis was performed. Characteristics of the cases and controls and the distribution of potential risk factors were described. A Student's t-test or ��2 test was AZD5363 research buy applied to examine the association of any potential risk factor and morbidity. The variables significantly associated with the outcomes (p multivariate regression model. Conditional logistic regression models were applied to examine any interaction between potential risk factors and morbidity. ORs and adjusted ORs (AORs) and their 95% CIs were calculated. Results Characteristics of participants In total, there were 298 patients admitted to the public hospitals over the study exposure period. Among these patients, 31 deceased, 25 under 18?years and 3 aboriginal patients were excluded, leading to 239 eligible cases to recruit. We interviewed 143 cases (60% of the total eligible patients) and 143 matched community controls (table 1). For the total sample of cases and controls, the mean age was 73?years (SD 21), 96% of European ethnicity; 63% were retired, 36% completed high school or higher education, 8% lived in institutions, and 30% were still in the workforce. For those who did not participate, 39% were female with a mean age of 69?years (SD 25). The main reason for not being able to participate Azastene (90% of the non-participants) was due to their incomplete hospital records or unknown address so that we could not reach them. The reason for cases refusing to participate included three patients with dementia, six who died close to the interview dates (not recorded in the collected hospital record data) and one non-English CP-673451 cost speaking case. Table?1 Characteristics of the participants and simple comparison between cases and controls Cases and controls were significantly different in some aspects of the characteristics, especially with respect to their living conditions, their support from family and community and health status. There were no obvious differences in terms of behaviour changes during heatwaves except for the use of air-conditioner (p