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The objectives of this study were to assess the prevalence/impact of SHS on preterm infants and children with BPD. Subjects (n?=?352) were recruited from the Johns Hopkins BPD outpatient clinic between January 2008 and August 2012. Second hand smoke exposure and respiratory morbidities were assessed through questionnaires and chart review. Twenty-eight percent of preterm infants with BPD were exposed to SHS in the home setting, despite having significant lung disease. SHS was associated with multiple measures of socio-economic status, including lower household income (P?Selleckchem Ibrutinib SHS were more likely to be prescribed inhaled corticosteroids (P?=?0.054) and were weaned off of supplemental oxygen over 2 months later (P?=?0.13) than infants not exposed to SHS. SHS exposure in preterm infants with BPD is common, even in those receiving supplemental oxygen and respiratory medications. Although there were no associations between respiratory outcomes and self-reported SHS exposure, trends toward increased use of inhaled steroids check details and a longer duration of supplemental oxygen use were noted. Further work is needed to determine more accurate means of assessing SHS risk in TRIB1 this vulnerable population. Pediatr Pulmonol. 2014; 49:173�C178. ? 2013 Wiley Periodicals, Inc. ""To determine the utility of overnight polysomnography (PSG) in assessing pulmonary reserve in stable preterm children with chronic lung disease (CLD). A retrospective review and descriptive study of overnight PSGs and clinic visits of preterm infants/children less than 3 years of age who were diagnosed with bronchopulmonary dysplasia at discharge from the hospital and enrolled in the Johns Hopkins CLD patient registry between 2008 and 2010. Sixty-two clinically stable patients underwent at least one overnight polysomnogram for clinical indications. The majority of patients were referred for oxygen titration (71%). PSGs from first studies revealed a mean respiratory disturbance index (RDI) of 8.2?��?10.1 events/hr and a mean O2 saturation (SaO2) nadir of 86.2?��?5.7%. In patients who underwent more than one PSG (n?=?23), a significant decrease in RDI (P?